E-cadherin antibody (AA 1-882)

Catalog No. ABIN514253

There are 2+ publications for this product available. The Rabbit Polyclonal anti-E-cadherin antibody is suitable to detect E-cadherin in samples from Human. It has been validated for WB.

Quick Overview for E-cadherin antibody (AA 1-882) (ABIN514253)

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E-cadherin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-E-cadherin Antibody

Binding Specificity: AA 1-882

Purpose: Rabbit polyclonal antibody raised against a full-length human CDH1 protein.

Sequence: MGPWSRSLSA LLLLLQVSSW LCQEPEPCHP GFDAESYTFT VPRRHLERGR VLGRVNFEDC TGRQRTAYFS LDTRFKVGTD GVITVKRPLR FHNPQIHFLV YAWDSTYRKF STKVTLNTVG HHHRPPPHQA SVSGIQAELL TFPNSSPGLR RQKRDWVIPP ISCPENEKGP FPKNLVQIKS NKDKEGKVFY SITGQGADTP PVGVFIIERE TGWLKVTEPL DRERIATYTL FSHAVSSNGN AVEDPMEILI TVTDQNDNKP EFTQEVFKGS VMEGALPGTS VMEVTATDAD DDVNTYNAAI AYTILSQDPE LPDKNMFTIN RNTGVISVVT TGLDRESFPT YTLVVQAADL QGEGLSTTAT AVITVTDTND NPPIFNPTTY KGQVPENEAN VVITTLKVTD ADAPNTPAWE AVYTILNDDG GQFVVTTNPV NNDGILKTAK GLDFEAKQQY ILHVAVTNVV PFEVSLTTST ATVTVDVLDV NEAPIFVPPE KRVEVSEDFG VGQEITSYTA QEPDTFMEQK ITYRIWRDTA NWLEINPDTG AISTRAELDR EDFEHVKNST YTALIIATDN GSPVATGTGT LLLILSDVND NAPIPEPRTI FFCERNPKPQ VINIIDADLP PNTSPFTAEL THGASANWTI QYNDPTQESI ILKPKMALEV GDYKINLKLM DNQNKDQVTT LEVSVCDCEG AAGVCRKAQP VEAGLQIPAI LGILGGILAL LILILLLLLF LRRRAVVKEP LLPPEDDTRD NVYYYDEEGG GEEDQDFDLS QLHRGLDARP EVTRNDVAPT LMSVPRYLPR PANPDEIGNF IDENLKAADT DPTAPPYDSL LVFDYEGSGS EAASLSSLNS SESDKDQDYD YLNEWGNRFK KLADMYGGGE DD

Cross-Reactivity: Human, Mouse

Characteristics: Antibody reactive against mammalian tissue lysate.

Immunogen: CDH1 (ENSP00000261769, 1 a.a. ~ 882 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-E-cadherin antibody (ABIN514253)

Yang, Zhang, Zhou, Jiang, Shen: "Transcription factor Snai1-1 induces osteosarcoma invasion and metastasis by inhibiting E-cadherin expression." in: Oncology letters, Vol. 8, Issue 1, pp. 193-197, (2014) (PubMed).

Wen, Chen, Chen, Chuang, Yang, Chow: "Development of an AlphaLISA assay to quantify serum core-fucosylated E-cadherin as a metastatic lung adenocarcinoma biomarker." in: Journal of proteomics, Vol. 75, Issue 13, pp. 3963-76, (2012) (PubMed).

Target Details for E-cadherin

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Alternative Name: CDH1

Background: Full Gene Name: cadherin 1, type 1, E-cadherin (epithelial)
Synonyms: Arc-1,CD324,CDHE,ECAD,LCAM,UVO

Gene ID: 999

NCBI Accession: NM_004360

Pathways: WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation