LATS2 antibody (pSer83)

Catalog No. ABIN531847

Product Details anti-LATS2 Antibody

Target: LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))

Binding Specificity: pSer83

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LATS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Mouse monoclonal antibody raised against synthetic phosphopeptide of LATS2.

Cross-Reactivity: Human

Characteristics: Phospho-LATS2 Ser83 Antibody detects phosphorylated recombinat LATS2 only when phosphorylated at serine83, by western blotting.

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S83 of human LATS2.

Clone: ST-3B11

Isotype: IgG2b

Application Details

Application Notes: Western Blot (1-2 μg/mL)
ELISA (1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 10 mM HEPES/KOH, 150 mM NaCl, pH 7.5 (50 % glycerol)

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-LATS2 antibody (ABIN531847)

Zhang, Iyer, Chowdhury, Ji, Xiao, Yang, Chen, Tsai, Dong: "KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis." in: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34069-77, (2012) (PubMed).

Xu, Stamenkovic, Yu: "CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma." in: Cancer research, Vol. 70, Issue 6, pp. 2455-64, (2010) (PubMed).

Lau, Murray, Houshmandi, Xu, Gutmann, Yu: "Merlin is a potent inhibitor of glioma growth." in: Cancer research, Vol. 68, Issue 14, pp. 5733-42, (2008) (PubMed).

Target Details for LATS2

Target: LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))

Alternative Name: LATS2 (LATS2 Products)

Synonyms: 4932411G09Rik antibody, AV277261 antibody, AW228608 antibody, KPM antibody, lats2 antibody, large tumor suppressor kinase 2 antibody, large tumor suppressor 2 antibody, LATS2 antibody, Lats2 antibody, lats2 antibody

Gene ID: 26524

NCBI Accession: NM_014572