TLR5 antibody (AA 700-800)

Catalog No. ABIN532010

Product Details anti-TLR5 Antibody

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Binding Specificity: AA 700-800

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against synthetic peptide of TLR5.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide corresponding to amino acids 700-800 of human TLR5.

Clone: 19D759-2

Isotype: IgG2a

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TLR5 antibody (ABIN532010)

Ha, Lee, Kim, Kwak, Kim, Lee, Rhee, Kim, Lee: "Stimulation by TLR5 modulates osteoclast differentiation through STAT1/IFN-beta." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1382-9, (2008) (PubMed).

Wong, Cheung, Ip, Lam: "Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils." in: American journal of respiratory cell and molecular biology, Vol. 37, Issue 1, pp. 85-96, (2007) (PubMed).

Crellin, Garcia, Hadisfar, Allan, Steiner, Levings: "Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 12, pp. 8051-9, (2005) (PubMed).

François, El Benna, Dang, Pedruzzi, Gougerot-Pocidalo, Elbim et al.: "Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 6, pp. 3633-42, (2005) (PubMed).

Miller, Sørensen, Liu, Jalian, Eshtiaghpour, Behmanesh, Chung, Starner, Kim, Sieling, Ganz, Modlin: "TGF-alpha regulates TLR expression and function on epidermal keratinocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 10, pp. 6137-43, (2005) (PubMed).

Target Details for TLR5

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Alternative Name: TLR5 (TLR5 Products)

Synonyms: SLEB1 antibody, TIL3 antibody, TLR-5 antibody, sleb1 antibody, til3 antibody, tlr-5 antibody, tlr5 antibody, toll like receptor 5 antibody, toll-like receptor 5 antibody, toll like receptor 5 L homeolog antibody, toll-like receptor 5b antibody, TLR5 antibody, Tlr5 antibody, tlr5.L antibody, tlr-5 antibody, tlr5b antibody

Gene ID: 7100

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades