TLR7 antibody (AA 451-500)

Catalog No. ABIN532922

Product Details anti-TLR7 Antibody

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Binding Specificity: AA 451-500

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Mouse monoclonal antibody raised against partial recombinant TLR7.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to amino acids 451-500 of human TLR7.

Clone: 4F4

Isotype: IgG1

Application Details

Application Notes: Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (10 % glycerol, 0.02 % sodium azide).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TLR7 antibody (ABIN532922)

Crozat, Beutler: "TLR7: A new sensor of viral infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 18, pp. 6835-6, (2004) (PubMed).

Lee, Chuang, Redecke, She, Pitha, Carson, Raz, Cottam: "Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 11, pp. 6646-51, (2003) (PubMed).

Horng, Barton, Flavell, Medzhitov: "The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors." in: Nature, Vol. 420, Issue 6913, pp. 329-33, (2002) (PubMed).

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7 (TLR7 Products)

Synonyms: TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody

Gene ID: 51284

NCBI Accession: NM_016562

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades