CYP3A5 antibody (C-Term)

Catalog No. ABIN533616

Product Details anti-CYP3A5 Antibody

Target: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Binding Specificity: C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP3A5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against synthetic peptide of CYP3A5.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to C-terminus of human CYP3A5.

Clone: F18 P3 B6

Isotype: IgG1

Application Details

Application Notes: Western Blot (1-2 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.08 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CYP3A5 antibody (ABIN533616)

Kim, Park, Lee, Kang, Park: "Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects." in: Journal of clinical pharmacology, Vol. 47, Issue 1, pp. 87-93, (2006) (PubMed).

McCune, Risler, Phillips, Thummel, Blough, Shen: "Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 33, Issue 7, pp. 1074-81, (2005) (PubMed).

Kumarakulasingham, Rooney, Dundas, Telfer, Melvin, Curran, Murray: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).

Target Details for CYP3A5

Target: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Alternative Name: CYP3A5 (CYP3A5 Products)

Synonyms: CP35 antibody, CYPIIIA5 antibody, P450PCN3 antibody, PCN3 antibody, cytochrome P450 family 3 subfamily A member 5 antibody, CYP3A5 antibody

Gene ID: 1577

Pathways: Steroid Hormone Biosynthesis