Thimet Oligopeptidase 1 antibody (AA 56-72)

Catalog No. ABIN534015

Product Details anti-Thimet Oligopeptidase 1 Antibody

Target: Thimet Oligopeptidase 1 (THOP1)

Binding Specificity: AA 56-72

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thimet Oligopeptidase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against synthetic peptide of THOP1.

Specificity: This antibody is specific to thimet oligopeptidase.

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to amino acids 56-72 of human THOP1.

Clone: 4D6

Isotype: IgG2b

Application Details

Application Notes: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400)
Western Blot (1:750-1:3000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Thimet Oligopeptidase 1 antibody (ABIN534015)

Yan, Shun-Chang, Li, Jie, Ya-Li, Ling-Xiong: "Topoisomerase II alpha expression and the benefit of adjuvant chemotherapy for postoperative patients with non-small cell lung cancer." in: BMC cancer, Vol. 10, pp. 621, (2010) (PubMed).

York, Mo, Lemerise, Zeng, Shen, Abraham, Saric, Goldberg, Rock: "The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation." in: Immunity, Vol. 18, Issue 3, pp. 429-40, (2003) (PubMed).

Saric, Beninga, Graef, Akopian, Rock, Goldberg: "Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase." in: The Journal of biological chemistry, Vol. 276, Issue 39, pp. 36474-81, (2001) (PubMed).

Target Details for Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Alternative Name: Thimet oligopeptidase (THOP1) (THOP1 Products)

Synonyms: EP24.15 antibody, MEPD_HUMAN antibody, MP78 antibody, TOP antibody, AI131655 antibody, AI327041 antibody, THOP1 antibody, thop1 antibody, MGC147297 antibody, LOC397806 antibody, mepd antibody, thimet oligopeptidase 1 antibody, thimet oligopeptidase 1 L homeolog antibody, thimet oligopeptidase antibody, peptidase antibody, Thimet oligopeptidase antibody, THOP1 antibody, Thop1 antibody, thop1 antibody, thop1.L antibody, Tc00.1047053506411.10 antibody, Tc00.1047053511237.10 antibody, Noca_4613 antibody, ANI_1_1400064 antibody, MBOO_RS10705 antibody, AOR_1_880174 antibody, AnaeK_0425 antibody, MPAL_RS03920 antibody, Hoch_5061 antibody, mepd antibody

Gene ID: 7064