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Kinesin (heavy chain) antibody

Reactivity: Pig ICC, IF Host: Mouse Monoclonal KN-02 unconjugated
Catalog No. ABIN535262
  • Target
    Kinesin (heavy chain)
    Reactivity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Pig
    Host
    • 3
    Mouse
    Clonality
    • 3
    Monoclonal
    Conjugate
    • 3
    Un-conjugated
    Application
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunocytochemistry (ICC), Immunofluorescence (IF)
    Purpose
    Mouse monoclonal antibody raised against native Kinesin (heavy chain).
    Specificity
    This antibody recognizes heavy chain of conventional kinesin associated withvesicles and with lower affinity with denaturated molecule. Epitope is located in coiled-coilstalk domain. It stains Western blots of kinesin-enriched preparations. Epitope mapping (by limited proteolysis of partially purified porcine kinesin) followed by immunoblotting has revealed that antibodies MAB3620, MAB3621 and MAB3622 react with differentsets of fragments. This antibody does not react with kinesin bound to taxol-stabilized microtubules.
    Cross-Reactivity
    Human, Mouse, Pig, Rat
    Immunogen
    Native purified porcine Kinesin (heavy chain).
    Clone
    KN-02
    Isotype
    IgM
  • Application Notes
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    In PBS, pH 7.4 (0.09 % sodium azide)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4°C. Do not freeze.
  • Malcová-Janatová, Richterová, Dráber, Hasek: "Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains." in: Folia microbiologica, Vol. 49, Issue 6, pp. 665-70, (2005) (PubMed).

    Mac?rek, Dráberová, Richterová, Böhm, Dráber: "Monoclonal antibodies KN-02 and KN-03 against the heavy chain of kinesin." in: Hybridoma and hybridomics, Vol. 21, Issue 6, pp. 457-62, (2003) (PubMed).

  • Target
    Kinesin (heavy chain)
    Synonyms
    KINH antibody, KNS antibody, KNS1 antibody, UKHC antibody, kinesin family member 5B antibody, kinesin family member 5C antibody, KIF5B antibody, Kif5c antibody
    Pathways
    Peptide Hormone Metabolism
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