Kinesin (heavy chain) antibody
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- Target
- Kinesin (heavy chain)
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Reactivity
- Pig
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Immunocytochemistry (ICC), Immunofluorescence (IF)
- Purpose
- Mouse monoclonal antibody raised against native Kinesin (heavy chain).
- Specificity
- This antibody recognizes heavy chain of conventional kinesin associated withvesicles and with lower affinity with denaturated molecule. Epitope is located in coiled-coilstalk domain. It stains Western blots of kinesin-enriched preparations. Epitope mapping (by limited proteolysis of partially purified porcine kinesin) followed by immunoblotting has revealed that antibodies MAB3620, MAB3621 and MAB3622 react with differentsets of fragments. This antibody does not react with kinesin bound to taxol-stabilized microtubules.
- Cross-Reactivity
- Human, Mouse, Pig, Rat
- Immunogen
- Native purified porcine Kinesin (heavy chain).
- Clone
- KN-02
- Isotype
- IgM
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- Application Notes
- The optimal working dilution should be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- In PBS, pH 7.4 (0.09 % sodium azide)
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C. Do not freeze.
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Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains." in: Folia microbiologica, Vol. 49, Issue 6, pp. 665-70, (2005) (PubMed).
: "Monoclonal antibodies KN-02 and KN-03 against the heavy chain of kinesin." in: Hybridoma and hybridomics, Vol. 21, Issue 6, pp. 457-62, (2003) (PubMed).
: "
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Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains." in: Folia microbiologica, Vol. 49, Issue 6, pp. 665-70, (2005) (PubMed).
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- Target
- Kinesin (heavy chain)
- Synonyms
- KINH antibody, KNS antibody, KNS1 antibody, UKHC antibody, kinesin family member 5B antibody, kinesin family member 5C antibody, KIF5B antibody, Kif5c antibody
- Pathways
- Peptide Hormone Metabolism
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