CD55 antibody (Biotin)

Catalog No. ABIN536215

Product Details anti-CD55 Antibody (Biotin)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD55 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against native CD55.

Specificity: This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 KDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.

Cross-Reactivity: Human, Non-Human Primate

Immunogen: Native purified CD55 from HPB-ALL human T cell line.

Clone: MEM-118

Isotype: IgM

Application Details

Application Notes: Flow Cytometry (1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

References for anti-CD55 antibody (Biotin) (ABIN536215)

Miwa, Maldonado, Zhou, Yamada, Gilkeson, Eisenberg, Song: "Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms." in: The American journal of pathology, Vol. 170, Issue 4, pp. 1258-66, (2007) (PubMed).

Abbott, Spendlove, Roversi, Fitzgibbon, Knott, Teriete, McDonnell, Handford, Lea: "Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55." in: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 22023-32, (2007) (PubMed).

VanLandingham, Cekic, Cutler, Hoffman, Stein: "Neurosteroids reduce inflammation after TBI through CD55 induction." in: Neuroscience letters, Vol. 425, Issue 2, pp. 94-8, (2007) (PubMed).

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55 / DAF (CD55 Products)

Synonyms: CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody

Gene ID: 1604

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity