Caspase 6 antibody (pSer257)

Catalog No. ABIN537573

Product Details anti-Caspase 6 Antibody

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Binding Specificity: pSer257

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of CASP6.

Cross-Reactivity: Human

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S257 of human CASP6.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Caspase 6 antibody (ABIN537573)

Kalinin, Kalinin, Aho, Uitto, Aho: "Breaking the connection: caspase 6 disconnects intermediate filament-binding domain of periplakin from its actin-binding N-terminal region." in: The Journal of investigative dermatology, Vol. 124, Issue 1, pp. 46-55, (2005) (PubMed).

Suzuki, Kusakai, Kishimoto, Shimojo, Miyamoto, Ogura, Ochiai, Esumi: "Regulation of caspase-6 and FLIP by the AMPK family member ARK5." in: Oncogene, Vol. 23, Issue 42, pp. 7067-75, (2004) (PubMed).

Horowitz, Patterson, Guillozet-Bongaarts, Reynolds, Carroll, Weintraub, Bennett, Cryns, Berry, Binder: "Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 36, pp. 7895-902, (2004) (PubMed).

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: Caspase-6 (CASP6 Products)

Synonyms: xCaspase-6 antibody, mch2 antibody, caspase-6 antibody, zgc:112960 antibody, CASP6 antibody, casp6 antibody, Mch2 antibody, mCASP-6 antibody, MCH2 antibody, caspase 6 L homeolog antibody, caspase 6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, group XIIA secretory phospholipase A2 antibody, caspase-6 antibody, casp6.L antibody, casp6 antibody, CASP6 antibody, CpipJ_CPIJ017008 antibody, Casp6 antibody

Gene ID: 839

Pathways: Apoptosis, Caspase Cascade in Apoptosis