TACR1 antibody (N-Term)

Catalog No. ABIN540271

Product Details anti-TACR1 Antibody

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of TACR1.

Specificity: This antibody is specific to human NK-1.

Cross-Reactivity: Guinea Pig, Human, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human TACR1.

Application Details

Application Notes: Immunohistochemistry (10 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TACR1 antibody (ABIN540271)

Hazlett, McClellan, Barrett, Liu, Zhang, Lighvani: "Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection." in: Investigative ophthalmology & visual science, Vol. 48, Issue 2, pp. 797-807, (2007) (PubMed).

Lai, Ho, Kilpatrick, Wang, Tuluc, Korchak, Douglas: "Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 20, pp. 7771-6, (2006) (PubMed).

Borghese, Werner, Topf, Baron, Henderson, Boehm, Blednov, Saad, Dai, Pearce, Harris, Homanics, Harrison: "An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice." in: The Journal of pharmacology and experimental therapeutics, Vol. 319, Issue 1, pp. 208-18, (2006) (PubMed).

Fong, Potts: "Neurokinin-1 receptor activation in Botzinger complex evokes bradypnoea." in: The Journal of physiology, Vol. 575, Issue Pt 3, pp. 869-85, (2006) (PubMed).

Target Details for TACR1

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Abstract: TACR1 Products

Synonyms: NK1R antibody, NKIR antibody, SPR antibody, TAC1R antibody, Nk1r antibody, Spr antibody, Tac1r antibody, nk1R antibody, Tacr1 antibody, ASPR antibody, tachykinin receptor 1 antibody, TACR1 antibody, Tacr1 antibody

Gene ID: 6869

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration