Aquaporin 4 antibody (C-Term)

Catalog No. ABIN540593

Product Details anti-Aquaporin 4 Antibody

Target: Aquaporin 4 (AQP4)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aquaporin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of AQP4.

Specificity: Identical to the related rat and mouse sequence.

Cross-Reactivity: Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to amino acids at C-terminus of human AQP4.

Isotype: IgG

Application Details

Application Notes: Western Blot (1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 0.9 mg NaCl, 0.2 mg Na₂HPO₄ (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-Aquaporin 4 antibody (ABIN540593)

Lennon, Kryzer, Pittock, Verkman, Hinson: "IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel." in: The Journal of experimental medicine, Vol. 202, Issue 4, pp. 473-7, (2005) (PubMed).

Nagelhus, Mathiisen, Ottersen: "Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1." in: Neuroscience, Vol. 129, Issue 4, pp. 905-13, (2004) (PubMed).

Amiry-Moghaddam, Otsuka, Hurn, Traystman, Haug, Froehner, Adams, Neely, Agre, Ottersen, Bhardwaj: "An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 4, pp. 2106-11, (2003) (PubMed).

Target Details for Aquaporin 4

Target: Aquaporin 4 (AQP4)

Alternative Name: Aquaporin-4 (AQP4 Products)

Synonyms: zgc:100922 antibody, si:ch211-192k9.1 antibody, AQP4 antibody, LOC100232616 antibody, HMIWC2 antibody, MIWC antibody, WCH4 antibody, AQP-4 antibody, AQP4.M23 antibody, MIWC2 antibody, Miwc antibody, aquaporin-4 antibody, aquaporin 4 antibody, aquaporin 4 L homeolog antibody, aqp4 antibody, AQP4 antibody, aqp4.L antibody, Aqp4 antibody

Gene ID: 361

Pathways: Sensory Perception of Sound