Neurofibromin 1 antibody (AA 27-41)

Catalog No. ABIN540660

Product Details anti-Neurofibromin 1 Antibody

Target: Neurofibromin 1 (NF1)

Binding Specificity: AA 27-41

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurofibromin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of NF1.

Sequence: QQNTHTKVST EHNKE

Specificity: This antibody is specific to neurofibromin.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to amino acids 27-41 of NF1.

Application Details

Application Notes: Western Blot (1:500-1:2000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Immunohistochemistry (Frozen sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Neurofibromin 1 antibody (ABIN540660)

Kuorilehto, Ekholm, Nissinen, Hietaniemi, Hiltunen, Paavolainen, Penttinen, Peltonen: "NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 3, pp. 363-70, (2006) (PubMed).

Zhu, Parada: "Neurofibromin, a tumor suppressor in the nervous system." in: Experimental cell research, Vol. 264, Issue 1, pp. 19-28, (2001) (PubMed).

Reed, Gutmann: "Tumorigenesis in neurofibromatosis: new insights and potential therapies." in: Trends in molecular medicine, Vol. 7, Issue 4, pp. 157-62, (2001) (PubMed).

Target Details for Neurofibromin 1

Target: Neurofibromin 1 (NF1)

Alternative Name: Neurofibromin (NF1 Products)

Synonyms: NFNS antibody, VRNF antibody, WSS antibody, CG8318 antibody, Dmel\\CG8318 antibody, NF-1 antibody, NF1 antibody, Nf-1 antibody, dNF1 antibody, nf1 antibody, fe06d03 antibody, hm:zehn0874 antibody, wu:fe06d03 antibody, zehn0874 antibody, AW494271 antibody, E030030H24Rik antibody, neurofibromin 1 antibody, Neurofibromin 1 antibody, neurofibromin 1a antibody, neurofibromin antibody, putative neurofibromin antibody, NF1 antibody, Nf1 antibody, nf1a antibody, LOC593418 antibody, LOC5570549 antibody, CpipJ_CPIJ011774 antibody, Smp_148460 antibody

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity