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Histone Cluster 2, H3c (HIST2H3C) (Lys27) antibody

HIST2H3C Reactivity: Human ELISA, WB, IHC, IP, ChIP, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN540989
  • Target See all Histone Cluster 2, H3c (HIST2H3C) products
    Histone Cluster 2, H3c (HIST2H3C)
    Binding Specificity
    • 2
    • 1
    Lys27
    Reactivity
    Human
    Host
    • 2
    • 1
    Rabbit
    Clonality
    • 2
    • 1
    Polyclonal
    Conjugate
    • 3
    Un-conjugated
    Application
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF)
    Purpose
    Rabbit polyclonal antibody raised against synthetic peptide of HIST2H3C.
    Specificity
    This antibody only recognizes ~17 KDa of Dimethylated HIST2H3C. It does not cross react to non-methylated H3 or mono-, Tri-methylated Histone H3.
    Cross-Reactivity
    Chicken, Cow, Human, Mouse, Rat
    Characteristics
    Antibody Reactive Against Synthetic Peptide.
    Immunogen
    A synthetic peptide corresponding to dimethyl lysine 27 of human HIST2H3C.
    Isotype
    IgG
  • Application Notes
    Western Blot (0.1-1 μg/mL)
    ELISA (0.01-0.1 μg/mL)
    Immunoprecipitation (2-5 μg/mL)
    Immunohistochemistry (1:100)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In TBS, pH 7.2 (BSA, 10 % Proclin300)
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C. For long term storage store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Seward, Cubberley, Kim, Schonewald, Zhang, Tripet, Bentley: "Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins." in: Nature structural & molecular biology, Vol. 14, Issue 3, pp. 240-2, (2007) (PubMed).

    Vakoc, Mandat, Olenchock, Blobel: "Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin." in: Molecular cell, Vol. 19, Issue 3, pp. 381-91, (2005) (PubMed).

  • Target
    Histone Cluster 2, H3c (HIST2H3C)
    Alternative Name
    HIST2H3C (HIST2H3C Products)
    Synonyms
    H3 antibody, H3.2 antibody, H3/M antibody, H3F2 antibody, H3FM antibody, H3FN antibody, histone cluster 2 H3 family member c antibody, HIST2H3C antibody
    Gene ID
    126961
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