ACVR2B antibody (N-Term)

Catalog No. ABIN542984

Product Details anti-ACVR2B Antibody

Target: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of ACVR2B.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human ACVR2B.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-ACVR2B antibody (ABIN542984)

Iwata, Hacia, Suzuki, Sanchez-Lara, Urata, Chai: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).

Martins da Silva, Bayne, Cambray, Hartley, McNeilly, Anderson: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." in: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).

Harrison, Gray, Fischer, Donaldson, Choe, Vale: "An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28036-44, (2004) (PubMed).

Casagrandi, Bearfield, Geary, Redman, Muttukrishna: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).

Target Details for ACVR2B

Target: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Alternative Name: Activin receptor type 2B (ACVR2B) (ACVR2B Products)

Synonyms: ACVR2B antibody, XAR1 antibody, actr-iib antibody, actriib antibody, ACTRIIB antibody, ActR-IIB antibody, HTX4 antibody, ActRIIB antibody, actr2b antibody, actrIIb antibody, wu:fj97d11 antibody, activin A receptor type 2B antibody, activin A receptor type 2B L homeolog antibody, activin A receptor type 2Ba antibody, activin receptor IIB antibody, ACVR2B antibody, acvr2b antibody, acvr2b.L antibody, Acvr2b antibody, acvr2ba antibody

Gene ID: 93

Pathways: Hormone Transport, Cancer Immune Checkpoints