PDGFA antibody (N-Term)

Catalog No. ABIN544636

Product Details anti-PDGFA Antibody

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of PDGFA.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PDGFA.

Application Details

Application Notes: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PDGFA antibody (ABIN544636)

Monje, Marinissen, Gutkind et al.: "Phosphorylation of the carboxyl-terminal transactivation domain of c-Fos by extracellular signal-regulated kinase mediates the transcriptional activation of AP-1 and cellular transformation induced ..." in: Molecular and cellular biology, Vol. 23, Issue 19, pp. 7030-43, (2003) (PubMed).

Müller, Richter, Rinas: "Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains." in: The Journal of biological chemistry, Vol. 278, Issue 20, pp. 18330-5, (2003) (PubMed).

Gianni, Zambrano, Bimonte, Minopoli, Mercken, Talamo, Scaloni, Russo: "Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway." in: The Journal of biological chemistry, Vol. 278, Issue 11, pp. 9290-7, (2003) (PubMed).

Target Details for PDGFA

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Alternative Name: PDGFA (PDGFA Products)

Synonyms: PDGF-A antibody, PDGF1 antibody, pdgfa antibody, pdgfa-2 antibody, zgc:100777 antibody, pdgf antibody, pdgf1 antibody, pdgf-a antibody, AA409063 antibody, CD142 antibody, Cf-3 antibody, Cf3 antibody, TF antibody, PDGFACP antibody, wu:fc32c12 antibody, zgc:153249 antibody, platelet derived growth factor subunit A antibody, platelet-derived growth factor alpha polypeptide a antibody, coagulation factor III antibody, platelet derived growth factor, alpha antibody, platelet derived growth factor subunit A S homeolog antibody, platelet-derived growth factor alpha polypeptide b antibody, PDGFA antibody, pdgfaa antibody, pdgfa antibody, F3 antibody, Pdgfa antibody, pdgfa.S antibody, pdgfab antibody

Gene ID: 5154

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling