PTPN1 antibody (AA 1-321)

Catalog No. ABIN545015

Product Details anti-PTPN1 Antibody

Target: PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))

Binding Specificity: AA 1-321

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit polyclonal antibody raised against partial recombinant PTPN1.

Cross-Reactivity: Human, Mouse

Immunogen: Recombinant protein corresponding to amino acids 1-321 of human PTPN1.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PTPN1 antibody (ABIN545015)

Ragab, Bodin, Viala, Chap, Payrastre, Ragab-Thomas: "The tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linking." in: The Journal of biological chemistry, Vol. 278, Issue 42, pp. 40923-32, (2003) (PubMed).

Sun, Fedorov, Lee, Guo, Shen, Lawrence, Almo, Zhang: "Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor." in: The Journal of biological chemistry, Vol. 278, Issue 14, pp. 12406-14, (2003) (PubMed).

Boute, Boubekeur, Lacasa, Issad: "Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells." in: EMBO reports, Vol. 4, Issue 3, pp. 313-9, (2003) (PubMed).

Target Details for PTPN1

Target: PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))

Alternative Name: PTPN1 (PTPN1 Products)

Synonyms: PTPN1 antibody, PTP1B antibody, PTP-1B antibody, PTP-HA2 antibody, Ptp antibody, ptp1b antibody, wu:fk54h03 antibody, CPTP1 antibody, protein tyrosine phosphatase, non-receptor type 1 antibody, protein tyrosine phosphatase, non-receptor type 1 L homeolog antibody, PTPN1 antibody, Ptpn1 antibody, ptpn1 antibody, ptpn1.L antibody

Gene ID: 5770

Pathways: TLR Signaling, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling