ATF4 antibody (Ser245)

Catalog No. ABIN545798

Product Details anti-ATF4 Antibody

Target: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Binding Specificity: Ser245

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of ATF4.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S245 of human ATF4.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-ATF4 antibody (ABIN545798)

Kakiuchi, Ishiwata, Nanko, Kunugi, Minabe, Nakamura, Mori, Fujii, Yamada, Yoshikawa, Kato: "Association analysis of ATF4 and ATF5, genes for interacting-proteins of DISC1, in bipolar disorder." in: Neuroscience letters, Vol. 417, Issue 3, pp. 316-21, (2007) (PubMed).

Gombart, Grewal, Koeffler: "ATF4 differentially regulates transcriptional activation of myeloid-specific genes by C/EBPepsilon and C/EBPalpha." in: Journal of leukocyte biology, Vol. 81, Issue 6, pp. 1535-47, (2007) (PubMed).

Jousse, Deval, Maurin, Parry, Chérasse, Chaveroux, Lefloch, Lenormand, Bruhat, Fafournoux: "TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15851-61, (2007) (PubMed).

Target Details for ATF4

Target: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Alternative Name: ATF4 (ATF4 Products)

Synonyms: CREB-2 antibody, CREB2 antibody, TAXREB67 antibody, TXREB antibody, ATF4 antibody, atf-4 antibody, creb-2 antibody, creb2 antibody, taxreb67 antibody, txreb antibody, atf4 antibody, wu:fj01c08 antibody, wu:fk30b04 antibody, zgc:85951 antibody, sb:eu681 antibody, wu:fb08f07 antibody, zgc:171702 antibody, Atf-4 antibody, C/ATF antibody, ATF4-I antibody, atf4-a antibody, atf4-b antibody, atf4-ii antibody, activating transcription factor 4 antibody, activating transcription factor 4 L homeolog antibody, activating transcription factor 4a antibody, activating transcription factor 4b antibody, activating transcription factor 4 S homeolog antibody, ATF4 antibody, atf4 antibody, Atf4 antibody, atf4.L antibody, atf4a antibody, atf4b antibody, atf4.S antibody

Gene ID: 468

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response