AIRE antibody

Catalog No. ABIN547689

Product Details anti-AIRE Antibody

Target: AIRE (Autoimmune Regulator (AIRE))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This AIRE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Goat polyclonal antibody raised against synthetic peptide of AIRE.

Sequence: C-KDVDLSQPRK GRKP

Specificity: This antibody is expected to recognize isoform 1 (NP_000374.1) only.

Cross-Reactivity: Dog, Human, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to human AIRE.

Application Details

Application Notes: ELISA (1:32000)
Western Blot (0.5-1 μg/mL)
Immunohistochemistry (2.5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In Tris saline, pH 7.3 (0.5 % BSA, 0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-AIRE antibody (ABIN547689)

Niki, Oshikawa, Mouri, Hirota, Matsushima, Yano, Han, Bando, Izumi, Matsumoto, Nakayama, Kuroda, Matsumoto: "Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice." in: The Journal of clinical investigation, Vol. 116, Issue 5, pp. 1292-301, (2006) (PubMed).

Target Details for AIRE

Target: AIRE (Autoimmune Regulator (AIRE))

Alternative Name: AIRE / APECED (AIRE Products)

Synonyms: AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody

Gene ID: 326

Pathways: Chromatin Binding