CCR6 antibody (AA 17-36)

Catalog No. ABIN549471

Product Details anti-CCR6 Antibody

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Binding Specificity: AA 17-36

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of CCR6.

Sequence: DYFVSVNTSY YSVDSEMLLC

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to amino acids 17-36 of human CCR6.

Application Details

Application Notes: Western Blot (1:500)
Immunoprecipitation (1:250)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In buffer containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CCR6 antibody (ABIN549471)

Westphal, Lügering, von Wedel, von Eiff, Maaser, Spahn, Heusipp, Schmidt, Herbst, Williams, Domschke, Kucharzik: "Resistance of chemokine receptor 6-deficient mice to Yersinia enterocolitica infection: evidence of defective M-cell formation in vivo." in: The American journal of pathology, Vol. 172, Issue 3, pp. 671-80, (2008) (PubMed).

Pötzl, Botteron, Tausch, Pedré, Mueller, Männel, Lechner: "Tracing functional antigen-specific CCR6 Th17 cells after vaccination." in: PLoS ONE, Vol. 3, Issue 8, pp. e2951, (2008) (PubMed).

Hirota, Yoshitomi, Hashimoto, Maeda, Teradaira, Sugimoto, Yamaguchi, Nomura, Ito, Nakamura, Sakaguchi, Sakaguchi: "Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model." in: The Journal of experimental medicine, Vol. 204, Issue 12, pp. 2803-12, (2007) (PubMed).

Target Details for CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Alternative Name: CD196 / CCR6 (CCR6 Products)

Synonyms: BN-1 antibody, C-C CKR-6 antibody, CC-CKR-6 antibody, CCR-6 antibody, CD196 antibody, CKR-L3 antibody, CKRL3 antibody, CMKBR6 antibody, DCR2 antibody, DRY6 antibody, GPR29 antibody, GPRCY4 antibody, STRL22 antibody, Cmkbr6 antibody, KY411 antibody, C-C motif chemokine receptor 6 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6 antibody, Ccr6 antibody

Gene ID: 1235

Pathways: cAMP Metabolic Process