GLRA1 antibody (N-Term)

Catalog No. ABIN550224

Product Details anti-GLRA1 Antibody

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of Glra1.

Specificity: Specific for the ~48k Glra1 and Glra2 in Western blots of rat spinal cord and brain stem and in cell extracts.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to N-terminus of rat Glra1.

Application Details

Application Notes: Immunohistochemistry (Frozen sections) (1:1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 5 mM ammonium bicarbonate

Storage: -20 °C

Storage Comment: Store at -20°C on dry atmosphere.
After reconstitution with PBS, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-GLRA1 antibody (ABIN550224)

Schofield, Jenkins, Harrison: "A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 34079-83, (2003) (PubMed).

Chatterton, Awobuluyi, Premkumar, Takahashi, Talantova, Shin, Cui, Tu, Sevarino, Nakanishi, Tong, Lipton, Zhang: "Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits." in: Nature, Vol. 415, Issue 6873, pp. 793-8, (2002) (PubMed).

Craig, Lichtman: "Getting a bead on receptor movements." in: Nature neuroscience, Vol. 4, Issue 3, pp. 219-20, (2001) (PubMed).

Target Details for GLRA1

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Alternative Name: Glycine receptor alpha-1 (GLRA1 Products)

Synonyms: GLYRA1 antibody, HKPX1 antibody, STHE antibody, [a]Z1 antibody, B230397M16Rik antibody, nmf11 antibody, oscillator antibody, ot antibody, spasmodic antibody, spd antibody, glycine receptor alpha 1 antibody, glycine receptor, alpha 1 antibody, glycine receptor, alpha 1 subunit antibody, GLRA1 antibody, Glra1 antibody, glra1 antibody

Gene ID: 25674

Pathways: Synaptic Membrane