GRIN2C antibody (N-Term)

Catalog No. ABIN550228

Product Details anti-GRIN2C Antibody

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Binding Specificity: N-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against partial recombinant Grin2c.

Specificity: Also labels the ~180k NR2A and the ~180k NR2B subunits of the NMDA receptor.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant protein corresponding to N-terminus rat Grin2c.

Application Details

Application Notes: Immunohistochemistry (Frozen sections) (1:1000-2000)
Immunofluorescence (1:1000-2000)
Immunoprecipitation (3 µL/200 μg lysate)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 5 mM ammonium bicarbonate

Storage: -20 °C

Storage Comment: Store at -20°C on dry atmosphere.
After reconstitution with 50 uL of PBS, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-GRIN2C antibody (ABIN550228)

Alvestad, Grosshans, Coultrap, Nakazawa, Yamamoto, Browning: "Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function." in: The Journal of biological chemistry, Vol. 278, Issue 13, pp. 11020-5, (2003) (PubMed).

Wenthold, Prybylowski, Standley, Sans, Petralia: "Trafficking of NMDA receptors." in: Annual review of pharmacology and toxicology, Vol. 43, pp. 335-58, (2003) (PubMed).

Carroll, Zukin: "NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity." in: Trends in neurosciences, Vol. 25, Issue 11, pp. 571-7, (2002) (PubMed).

Target Details for GRIN2C

Target: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Alternative Name: NMDA Receptor 2C (GRIN2C Products)

Synonyms: GRIN2C antibody, NMDAR2C antibody, il12rb2l antibody, il-12rb2.b antibody, nr2c antibody, GluN2C antibody, NR2C antibody, glutamate ionotropic receptor NMDA type subunit 2C antibody, interleukin 12 receptor, beta 2a, like antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2C antibody, glutamate receptor, ionotropic, NMDA2C (epsilon 3) antibody, GRIN2C antibody, il12rb2l antibody, grin2c.S antibody, grin2c antibody, Grin2c antibody

Gene ID: 24411

Pathways: Synaptic Membrane