TYROBP antibody

Catalog No. ABIN550357

Product Details anti-TYROBP Antibody

Target: TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYROBP antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against a recombinant DAP12.

Cross-Reactivity: Mouse

Immunogen: Recombinant protein corresponding to DAP12.

Isotype: IgG

Application Details

Application Notes: Immunoprecipitation (2-4 μg/mg)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Buffer: In PBS (0.08 % sodium azide)

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TYROBP antibody (ABIN550357)

Lanier, Bakker: "The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function." in: Immunology today, Vol. 21, Issue 12, pp. 611-4, (2001) (PubMed).

Paloneva, Kestilä, Wu, Salminen, Böhling, Ruotsalainen, Hakola, Bakker, Phillips, Pekkarinen, Lanier, Timonen, Peltonen: "Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts." in: Nature genetics, Vol. 25, Issue 3, pp. 357-61, (2000) (PubMed).

Tomasello, Desmoulins, Chemin, Guia, Cremer, Ortaldo, Love, Kaiserlian, Vivier: "Combined natural killer cell and dendritic cell functional deficiency in KARAP/DAP12 loss-of-function mutant mice." in: Immunity, Vol. 13, Issue 3, pp. 355-64, (2000) (PubMed).

Target Details for TYROBP

Target: TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))

Alternative Name: TYROBP / DAP12 (TYROBP Products)

Synonyms: TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody