TMPRSS2 antibody (N-Term)

Catalog No. ABIN5514432

This Rabbit Polyclonal antibody specifically detects TMPRSS2 in WB. It exhibits reactivity toward Human.

Quick Overview for TMPRSS2 antibody (N-Term) (ABIN5514432)

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMPRSS2 Antibody

Binding Specificity: N-Term

Purpose: TMPRSS2 Antibody - N-terminal region

Sequence: YYENHGYQPE NPYPAQPTVV PTVYEVHPAQ YYPSPVPQYA PRVLTQASNP

Characteristics: This is a rabbit polyclonal antibody against TMPS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TMPS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74292-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Alternative Name: TMPRSS2

Background:

Background Information: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: transmembrane serine protease 2

Alternative Symbols: PRSS10

Protein Name: transmembrane protease serine 2

Molecular Weight: 54kDa

Gene ID: 7113

NCBI Accession: NP_005647

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interactome