AKAP12 antibody (Middle Region)

Catalog No. ABIN5514477

Product Details anti-AKAP12 Antibody

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLSSQERMKV QGSPLKKLFT STGLKKLSGK KQKGKRGGGD EESGEHTQVP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of human AKAP12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AKAP12

Target: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Alternative Name: AKAP12 (AKAP12 Products)

Synonyms: akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, AKAP12 antibody, AI317366 antibody, SSeCKS antibody, Srcs5 antibody, Tsga12 antibody, AKAP12A antibody, AKAP12B antibody, AKAP12G antibody, AKAP250 antibody, A kinase (PRKA) anchor protein 12b antibody, A-kinase anchoring protein 12 antibody, A kinase (PRKA) anchor protein (gravin) 12 antibody, akap12b antibody, AKAP12 antibody, Akap12 antibody

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Alias Symbols: SSeCKS, AKAP250

Protein Size: 1684

Gene ID: 9590

NCBI Accession: NM_005100, NP_005091

Pathways: cAMP Metabolic Process