AKR7A2 antibody (Middle Region)

Catalog No. ABIN5514485

Product Details anti-AKR7A2 Antibody

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR7A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YSDGQSETIL GGLGLGLGGG DCRVKIATKA NPWDGKSLKP DSVRSQLETS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKR7A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AKR7A2

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Alternative Name: AKR7A2 (AKR7A2 Products)

Synonyms: AFAR antibody, AFAR1 antibody, AFB1-AR1 antibody, AKR7 antibody, Aiar antibody, akr7a2 antibody, aldo-keto reductase family 7 member A2 antibody, aldo-keto reductase family 7, member A2 antibody, aldo-keto reductase family 7, member A2 L homeolog antibody, AKR7A2 antibody, Akr7a2 antibody, akr7a2.L antibody

Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.

Alias Symbols: AFAR, AKR7, AFAR1, AFB1-AR1

Protein Size: 167

Gene ID: 8574

NCBI Accession: NM_003689, NP_003680

UniProt: O43488