ADCY4 antibody (Middle Region)

Catalog No. ABIN5514525

Product Details anti-ADCY4 Antibody

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IGQNRRNEDL YHQSYECVCV LFASVPDFKE FYSESNINHE GLECLRLLNE

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADCY4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADCY4

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Alternative Name: ADCY4 (ADCY4 Products)

Synonyms: ADCY4 antibody, mKIAA4004 antibody, AC4 antibody, adenylate cyclase 4 antibody, ADCY4 antibody, Adcy4 antibody

Background: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.

Alias Symbols: AC4

Protein Size: 760

Gene ID: 196883

NCBI Accession: NM_001198568, NP_001185497

UniProt: B4DSJ6

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma