PLG antibody (Middle Region)

Catalog No. ABIN5514605

Product Details anti-PLG Antibody

Target: PLG (Plasminogen (PLG))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Pig, Cow, Goat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLG antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TAPPELTPVV QDCYHGDGQS YRGTSSTTTT GKKCQSWSSM TPHRHQKTPE

Predicted Reactivity: Cow: 92%, Dog: 92%, Goat: 92%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 85%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against PLMN. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PLMN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLG

Target: PLG (Plasminogen (PLG))

Alternative Name: PLMN (PLG Products)

Synonyms: wu:fb70e09 antibody, PLG antibody, LPA antibody, plg antibody, Ab1-346 antibody, AI649309 antibody, Pg antibody, plasminogen antibody, plg antibody, PLG antibody, Plg antibody

Background: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PLG,

Protein Interaction Partner: RELA, SUZ12, RNF2, HSPD1, HSPB1, HSPA1A, ACTB, YTHDC1, CYFIP2, PRDX4, SMAD4, SMAD3, EP300, MAPK14, RBBP6, RAP2A, CDCP1, RUVBL1, TFPI2, NGF, CHGA, SERPING1, SERPINB13, CPB2, SERPINI1, F2RL1, LAMA3, MEP1A, PCOLCE, AMOT, SERPINF2, KNG1, F10, C7, PLAU, THBS1,

Protein Size: 810

Gene ID: 5340

NCBI Accession: NP_000292

UniProt: P00747

Pathways: Complement System, Lipid Metabolism