DOK3 antibody (C-Term)

Catalog No. ABIN5514711

Product Details anti-DOK3 Antibody

Target: DOK3 (Docking Protein 3 (DOK3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLEASPTLHG GEPEPHEGPG SRSPTTSPIY HNGQDLSWPG PANDSTLEAQ

Characteristics: This is a rabbit polyclonal antibody against DOK3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DOK3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOK3

Target: DOK3 (Docking Protein 3 (DOK3))

Alternative Name: DOK3 (DOK3 Products)

Synonyms: DOK3 antibody, DOKL antibody, AI450713 antibody, Dokl antibody, docking protein 3 antibody, DOK3 antibody, Dok3 antibody

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. It may modulate ABL1 function.

Alias Symbols: DOK3,

Protein Interaction Partner: RBPMS, TRAF1, YWHAE, LRRK1, GRB2, BLNK, INPP5D, ABL1, LYN, RET, LCK, FYN, CSK,

Protein Size: 496

Gene ID: 79930

UniProt: Q7L591