USP14 antibody (C-Term)

Catalog No. ABIN5514794

Product Details anti-USP14 Antibody

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP14 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FKDLEDKKVN QQPNTSDKKS SPQKEVKYEP FSFADDIGSN NCGYYDLQAV

Characteristics: This is a rabbit polyclonal antibody against UBP14. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBP14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Alternative Name: UBP14 (USP14 Products)

Synonyms: TGT antibody, DDBDRAFT_0202821 antibody, DDBDRAFT_0237695 antibody, DDB_0202821 antibody, DDB_0237695 antibody, 2610005K12Rik antibody, 2610037B11Rik antibody, AW107924 antibody, C78769 antibody, ax antibody, zgc:55949 antibody, wu:fk63d09 antibody, MGC81945 antibody, tgt antibody, MGC69343 antibody, USP14 antibody, ubiquitin specific peptidase 14 antibody, peptidase C19 family protein antibody, ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) antibody, ubiquitin specific protease 14 antibody, ubiquitin specific peptidase 14 S homeolog antibody, universal stress protein antibody, Ubiquitin carboxyl-terminal hydrolase 14 antibody, USP14 antibody, usp14 antibody, Usp14 antibody, Bm1_28765 antibody, usp14.S antibody, RR_RS06480 antibody, usp-14 antibody

Background: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alias Symbols: USP14, TGT,

Protein Interaction Partner: UBC, UBP6, PSMD2, HTT, ERN1, CLB1, SHFM1, RPL23, RPL30, RAP1GDS1, GSS, ECHS1, CNDP2, RNF11, PFAS, HNRNPK, VPS37B, UNC45A, WDR12, XPO7, PSMD14, XPO1, UBE3A, UBE2N, PSMD13, PSMD12, PSMD7, PSMC6, PSMC4, PSMC3, USP28, USP21, USP15, PSMD4, PSMA2, RAD23A, PSMC5

Protein Size: 494

Gene ID: 9097

NCBI Accession: NP_005142

UniProt: P54578