Lipocalin 2 antibody (Middle Region)

Catalog No. ABIN5514918

Product Details anti-Lipocalin 2 Antibody

Target: Lipocalin 2 (LCN2)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipocalin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LIPAPPLSKV PLQQNFQDNQ FQGKWYVVGL AGNAILREDK DPQKMYATIY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LCN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lipocalin 2

Target: Lipocalin 2 (LCN2)

Alternative Name: LCN2 (LCN2 Products)

Synonyms: LCN2 antibody, 24p3 antibody, MSFI antibody, NGAL antibody, AW212229 antibody, Sip24 antibody, lipocalin 2 antibody, LCN2 antibody, Lcn2 antibody

Background: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.

Alias Symbols: p25, 24p3, MSFI, NGAL

Protein Size: 200

Gene ID: 3934

NCBI Accession: NP_005555

UniProt: X6R8F3

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis