STAG2 antibody (N-Term)

Catalog No. ABIN5514998

Product Details anti-STAG2 Antibody

Target: STAG2 (Stromal Antigen 2 (STAG2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAG2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EDIEGKNQKQ GKGKTCKKGK KGPAEKGKGG NGGGKPPSGP NRMNGHHQQN

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STAG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAG2

Target: STAG2 (Stromal Antigen 2 (STAG2))

Alternative Name: STAG2 (STAG2 Products)

Synonyms: SA-2 antibody, SA2 antibody, SCC3B antibody, bA517O1.1 antibody, RGD1562042 antibody, STAG2 antibody, stag2 antibody, 9230105L23Rik antibody, B230112I07Rik antibody, SAP2 antibody, XSA2 antibody, sa2 antibody, sa2-a antibody, stromal antigen 2 antibody, cohesin subunit SA-2 antibody, STAG2 antibody, Stag2 antibody, LOC100175748 antibody, LOC100301585 antibody, LOC100565959 antibody, stag2 antibody

Background: The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: SA2, SA-2, SCC3B, bA517O1.1

Protein Size: 1231

Gene ID: 10735

NCBI Accession: NM_001042749, NP_001036214

UniProt: Q8N3U4

Pathways: Stem Cell Maintenance