SYN2 antibody (Middle Region)

Catalog No. ABIN5515341

Product Details anti-SYN2 Antibody

Target: SYN2 (Synapsin II (SYN2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QRPLTTQQPQ SGTLKDPDSS KTPPQRPPPQ GGPGQPQGMQ PPGKVLPPRR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SYN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYN2

Target: SYN2 (Synapsin II (SYN2))

Alternative Name: SYN2 (SYN2 Products)

Synonyms: synII antibody, synIIa antibody, synIIb antibody, syn1 antibody, syn2 antibody, zgc:92311 antibody, MGC115109 antibody, SYN2 antibody, SYNII antibody, SYNIIa antibody, SYNIIb antibody, 2900074L19Rik antibody, AI836018 antibody, AI841723 antibody, synapsin II L homeolog antibody, synapsin II antibody, synapsin IIa antibody, synapsin II S homeolog antibody, synapsin-2 antibody, syn2.L antibody, SYN2 antibody, syn2a antibody, syn2.S antibody, EDI_190690 antibody, Syn2 antibody

Background: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction.

Alias Symbols: SYNII

Protein Size: 582

Gene ID: 6854

NCBI Accession: NP_003169

UniProt: Q92777