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ASIP antibody (Middle Region)

ASIP Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5515388
  • Target See all ASIP Antibodies
    ASIP (Agouti Signaling Protein (ASIP))
    Binding Specificity
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 25
    • 2
    Human
    Host
    • 26
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASIP antibody is un-conjugated
    Application
    • 16
    • 8
    • 5
    • 4
    • 2
    Western Blotting (WB)
    Sequence
    CFFTANSHLP PEEKLRDDRS LRSNSSVNLL DVPSVSIVAL NKKSKQIGRK
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ASIP
    Top Product
    Discover our top product ASIP Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ASIP (Agouti Signaling Protein (ASIP))
    Alternative Name
    ASIP (ASIP Products)
    Synonyms
    AGSW antibody, AGTI antibody, AGTIL antibody, ASP antibody, SHEP9 antibody, ASIP antibody, AA960621 antibody, AI256638 antibody, D8Ertd580e antibody, PAR-3 antibody, Par3 antibody, Pard3a antibody, agouti signaling protein antibody, par-3 family cell polarity regulator antibody, ASIP antibody, Asip antibody, asip antibody, Pard3 antibody
    Background
    In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

    Alias Symbols: ASP, AGSW, AGTI, AGTIL, SHEP9

    Protein Size: 132
    Gene ID
    434
    NCBI Accession
    NM_001672, NP_001663
    UniProt
    P42127
    Pathways
    Cell-Cell Junction Organization, Feeding Behaviour
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