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ASIP antibody (Middle Region)
ASIP
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ASIP Antibody
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Target
See all ASIP Antibodies
ASIP
(Agouti Signaling Protein (ASIP))
Binding Specificity
All epitopes for ASIP antibodies
Middle Region
Reactivity
All reactivities for ASIP antibodies
Human
Host
All hosts for ASIP antibodies
Rabbit
Clonality
All clonalities for ASIP antibodies
Polyclonal
Conjugate
All conjugates for ASIP antibodies
This ASIP antibody is un-conjugated
Application
All applications for ASIP antibodies
Western Blotting (WB)
Sequence
CFFTANSHLP PEEKLRDDRS LRSNSSVNLL DVPSVSIVAL NKKSKQIGRK
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ASIP
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for ASIP
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Target
ASIP
(Agouti Signaling Protein (ASIP))
Alternative Name
ASIP (ASIP Products )
Synonyms
AGSW antibody, AGTI antibody, AGTIL antibody, ASP antibody, SHEP9 antibody, ASIP antibody, AA960621 antibody, AI256638 antibody, D8Ertd580e antibody, PAR-3 antibody, Par3 antibody, Pard3a antibody, agouti signaling protein antibody, par-3 family cell polarity regulator antibody, ASIP antibody, Asip antibody, asip antibody, Pard3 antibody
Background
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. Alias Symbols: ASP, AGSW, AGTI, AGTIL, SHEP9 Protein Size: 132
Gene ID
434
NCBI Accession
NM_001672 , NP_001663
UniProt
P42127
Pathways
Cell-Cell Junction Organization , Feeding Behaviour
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