HIST2H2AA3 antibody (N-Term)

Catalog No. ABIN5515425

Product Details anti-HIST2H2AA3 Antibody

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST2H2AA3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRGKQGGKAR AKAKSRSSRA GLQFPVGRVH RLLRKGNYAE RVGAGAPVYM

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HIST2H2AA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIST2H2AA3

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Alternative Name: HIST2H2AA3 (HIST2H2AA3 Products)

Synonyms: H2A antibody, H2A.2 antibody, H2A/O antibody, H2A/q antibody, H2AFO antibody, H2a-615 antibody, HIST2H2AA antibody, Hist2h2aa antibody, Hist2h2aa1 antibody, histone cluster 2 H2A family member a3 antibody, histone cluster 2 H2A family member A3 antibody, HIST2H2AA3 antibody, Hist2h2aa3 antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy.

Alias Symbols: H2A/R

Protein Size: 130

Gene ID: 723790

NCBI Accession: NM_001040874, NP_001035807

UniProt: Q6FI13

Pathways: Telomere Maintenance