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HTRA1 antibody (Middle Region)
HTRA1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HTRA1 Antibody
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Target
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HTRA1
(HtrA Serine Peptidase 1 (HTRA1))
Binding Specificity
All epitopes for HTRA1 antibodies
Middle Region
Reactivity
All reactivities for HTRA1 antibodies
Human
Host
All hosts for HTRA1 antibodies
Rabbit
Clonality
All clonalities for HTRA1 antibodies
Polyclonal
Conjugate
All conjugates for HTRA1 antibodies
This HTRA1 antibody is un-conjugated
Application
All applications for HTRA1 antibodies
Western Blotting (WB)
Sequence
CQLRAASRRS ERLHRPPVIV LQRGACGQGQ EDPNSLRHKY NFIADVVEKI
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HTRA1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for HTRA1
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Target
HTRA1
(HtrA Serine Peptidase 1 (HTRA1))
Alternative Name
HTRA1 (HTRA1 Products )
Synonyms
htra1 antibody, zgc:92029 antibody, zgc:172061 antibody, l56 antibody, htra antibody, Xhtra1 antibody, prss11 antibody, MGC145723 antibody, ARMD7 antibody, CARASIL antibody, HtrA antibody, L56 antibody, ORF480 antibody, PRSS11 antibody, AI429470 antibody, HTRA antibody, Prss11 antibody, RSPP11 antibody, HTRA1 antibody, HtrA serine peptidase 1a antibody, HtrA serine peptidase 1 antibody, HtrA serine peptidase 1b antibody, Serine protease HTRA1 antibody, HtrA serine peptidase 1 S homeolog antibody, htra1a antibody, HTRA1 antibody, htra1b antibody, htra1 antibody, Htra1 antibody, htra1.S antibody
Background
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. Alias Symbols: L56, HtrA, ARMD7, ORF480, PRSS11, CARASIL, CADASIL2 Protein Size: 480
Gene ID
5654
NCBI Accession
NM_002775 , NP_002766
UniProt
Q92743
Pathways
Growth Factor Binding
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