Cullin 3 antibody (C-Term)

Catalog No. ABIN5515435

Product Details anti-Cullin 3 Antibody

Target: Cullin 3 (CUL3)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VNDQFTSKLH RVKIQTVAAK QGESDPERKE TRQKVDDDRK HEIEAAIVRI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CUL3. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CUL3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cullin 3

Target: Cullin 3 (CUL3)

Alternative Name: CUL3 (CUL3 Products)

Synonyms: CUL-3 antibody, Cullin-3 antibody, CUL-3-A antibody, Cullin-3-A antibody, cul3 antibody, cul3a antibody, CUL-3-B antibody, Cullin-3-B antibody, cul3b antibody, wu:fc37e01 antibody, CUL3 antibody, ATCUL3 antibody, ATCUL3A antibody, CUL3A antibody, T24P13.25 antibody, cullin 3 antibody, cullin 3A antibody, PHA2E antibody, AI467304 antibody, AW146203 antibody, mKIAA0617 antibody, cullin 3 antibody, cullin 3 L homeolog antibody, cullin 3 S homeolog antibody, cullin-3 antibody, Cullin-3 (CUL-3) antibody, cullin 3a antibody, CULlin antibody, CUL3 antibody, cul3 antibody, cul3.L antibody, cul3.S antibody, PTRG_11586 antibody, Smp_117580 antibody, cul3a antibody, Cul3 antibody, cul-3 antibody

Background: This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alias Symbols: KIAA0617

Protein Interaction Partner: KCTD6, ABTB1, CUL5, DEK, UBE2D1, UBC, RBX1, KEAP1, NCOA3, TNFAIP1, NEDD8, KCTD13, CUL3, SPOP, KLHL3, RHOA, ZMAT4, GMCL1, KLHL12, KCTD9, KLHL2, KLHL22, BTBD2, BTBD1, WDFY4, WDR48, LRRC7, KLHL42, WDR35, LRFN2, WDTC1, TRIM32, NLRP1, DMWD, HIRA, PHIP, PAK1IP1

Protein Size: 768

Gene ID: 8452

UniProt: Q13618

Pathways: M Phase