SHPK antibody (Middle Region)

Catalog No. ABIN5515444

Product Details anti-SHPK Antibody

Target: SHPK (Sedoheptulokinase (SHPK))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHPK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SDQNAASWGY FNTQSQSWNV ETLRSSGFPV HLLPDIAEPG SVAGRTSHMW

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SHPK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHPK

Target: SHPK (Sedoheptulokinase (SHPK))

Alternative Name: SHPK (SHPK Products)

Synonyms: SHPK antibody, CARKL antibody, carkl antibody, MGC154818 antibody, SHK antibody, 4930431K22Rik antibody, AI194947 antibody, AW260459 antibody, Carkl antibody, sedoheptulokinase antibody, sedoheptulokinase S homeolog antibody, Sedoheptulokinase antibody, SHPK antibody, shpk.S antibody, Plabr_2171 antibody, shpk antibody, Shpk antibody

Background: The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

Alias Symbols: SHK, CARKL

Protein Size: 167

Gene ID: 23729

NCBI Accession: NM_013276, NP_037408

UniProt: Q9UHJ6

Pathways: Cellular Response to Molecule of Bacterial Origin