SSTR5 antibody (Middle Region)

Catalog No. ABIN5515665

This Rabbit Polyclonal antibody specifically detects SSTR5 . It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep and Zebrafish (Danio rerio).

Quick Overview for SSTR5 antibody (Middle Region) (ABIN5515665)

Target: SSTR5 (Somatostatin Receptor 5 (SSTR5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSTR5 antibody is un-conjugated

Application: Please inquire

Product Details anti-SSTR5 Antibody

Binding Specificity: Middle Region

Sequence: FAPLLVICLC YLLIVVKVRA AGVRVGCVRR RSERKVTRMV LVVVLVFAGC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 77%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SSR5

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSTR5

Target: SSTR5 (Somatostatin Receptor 5 (SSTR5))

Alternative Name: SSTR5

Background: Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.

Alias Symbols: SS-5-R

Protein Interaction Partner: UBC, SST, GOPC, ADCY10, PDZK1, CORT, PEX5, SSTR5, SSTR1, DRD2,

Protein Size: 364

Gene ID: 6755

NCBI Accession: NM_001053, NP_001044

UniProt: P35346

Pathways: Carbohydrate Homeostasis