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AEN antibody (N-Term)
AEN
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AEN Antibody
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Target
See all AEN Antibodies
AEN
(Apoptosis Enhancing Nuclease (AEN))
Binding Specificity
All epitopes for AEN antibodies
N-Term
Reactivity
Human
Host
All hosts for AEN antibodies
Rabbit
Clonality
All clonalities for AEN antibodies
Polyclonal
Conjugate
All conjugates for AEN antibodies
This AEN antibody is un-conjugated
Application
All applications for AEN antibodies
Western Blotting (WB)
Sequence
REAPESAQCL CPSLTIPNAK DVLRKRHKRR SRQHQRFMAR KALLQEQGLL
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human AEN
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for AEN
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Target
AEN
(Apoptosis Enhancing Nuclease (AEN))
Alternative Name
AEN (AEN Products )
Synonyms
AEN antibody, ISG20L1 antibody, xaen antibody, isg20l1 antibody, MGC147218 antibody, pp12744 antibody, 2700083B06Rik antibody, Isg20l1 antibody, RGD1305051 antibody, apoptosis enhancing nuclease antibody, apoptosis enhancing nuclease L homeolog antibody, AEN antibody, aen.L antibody, aen antibody, Aen antibody
Background
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis. Alias Symbols: ISG20L1, pp12744 Protein Size: 325
Gene ID
64782
NCBI Accession
NM_022767 , NP_073604
UniProt
Q8WTP8
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