CLEC4E antibody (Middle Region)

Catalog No. ABIN5515840

Product Details anti-CLEC4E Antibody

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC4E antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EGQWQWVDGT PLTKSLSFWD VGEPNNIATL EDCATMRDSS NPRQNWNDVT

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLEC4E

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLEC4E

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Alternative Name: CLEC4E (CLEC4E Products)

Synonyms: CLECSF9 antibody, MINCLE antibody, C86253 antibody, Clecsf9 antibody, Mincle antibody, CLEC4E antibody, C-type lectin domain family 4 member E antibody, C-type lectin domain family 4, member e antibody, C-type lectin domain family 4, member E antibody, CLEC4E antibody, Clec4e antibody, LOC611538 antibody

Background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Alias Symbols: MINCLE, CLECSF9

Protein Size: 167

Gene ID: 26253

NCBI Accession: NM_014358, NP_055173

UniProt: Q9ULY5