COL4a5 antibody (Middle Region)

Catalog No. ABIN5515938

Product Details anti-COL4a5 Antibody

Target: COL4a5 (COL4A5) (Collagen, Type IV, alpha 5 (COL4A5))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL4a5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGPPGSPGDK GLQGEQGVKG DKGDTCFNCI GTGISGPPGQ PGLPGLPGPP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COL4A5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COL4a5

Target: COL4a5 (COL4A5) (Collagen, Type IV, alpha 5 (COL4A5))

Alternative Name: COL4A5 (COL4A5 Products)

Synonyms: ASLN antibody, ATS antibody, CA54 antibody, RGD1565499 antibody, col4a5 antibody, fj65e07 antibody, im:7157877 antibody, si:ch211-174g17.1 antibody, wu:fj65e07 antibody, collagen type IV alpha 5 chain antibody, collagen, type IV, alpha 5 antibody, collagen, type IV, alpha 1 antibody, COL4A5 antibody, Col4a5 antibody, col4a1 antibody, LOC100285389 antibody

Background: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.

Alias Symbols: ATS, ASLN, CA54

Protein Size: 695

Gene ID: 1287

NCBI Accession: NM_000495, NP_000486

UniProt: Q49AM6

Pathways: Skeletal Muscle Fiber Development