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FBXO2 antibody (Middle Region)
FBXO2
Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FBXO2 Antibody
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Target
See all FBXO2 Antibodies
FBXO2
(F-Box Protein 2 (FBXO2))
Binding Specificity
All epitopes for FBXO2 antibodies
Middle Region
Reactivity
All reactivities for FBXO2 antibodies
Human, Mouse, Rat, Horse, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio)
Host
All hosts for FBXO2 antibodies
Rabbit
Clonality
All clonalities for FBXO2 antibodies
Polyclonal
Conjugate
All conjugates for FBXO2 antibodies
This FBXO2 antibody is un-conjugated
Application
All applications for FBXO2 antibodies
Western Blotting (WB)
Sequence
HGGDGWRVEE LPGDSGVEFT HDESVKKYFA SSFEWCRKAQ VIDLQAEGYW
Predicted Reactivity
Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%
Characteristics
This is a rabbit polyclonal antibody against FBXO2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human FBXO2
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for FBXO2
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Target
FBXO2
(F-Box Protein 2 (FBXO2))
Alternative Name
FBXO2 (FBXO2 Products )
Synonyms
FBG1 antibody, FBX2 antibody, Fbs1 antibody, NFB42 antibody, OCP1 antibody, Fbs2 antibody, Prpl4 antibody, F-box protein 2 antibody, FBXO2 antibody, Fbxo2 antibody
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. Alias Symbols: FBXO2, FBX2, Protein Interaction Partner: SKP1, CUL1, IQCB1, UBE2L3, UBE2E1, UBE2D3, UBE2D2, UBE2D1, ITGB1, TOR1A, AHSG, ANAPC2, KIAA0368, RBX1, CUL7, GJB2, BACE1, MGMT, STUB1, VCP, Protein Size: 296
Gene ID
26232
NCBI Accession
NM_012168 , NP_036300
UniProt
Q9UK22
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