Fatty Acid Synthase antibody (Middle Region)

Catalog No. ABIN5516021

Product Details anti-Fatty Acid Synthase Antibody

Target: Fatty Acid Synthase (FASN)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SENGNLVVSG KVYQWDDPDP RLFDHPESPT PNPTEPLFLA QAEVYKELRL

Characteristics: This is a rabbit polyclonal antibody against FASN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FASN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: FASN (FASN Products)

Synonyms: FAS antibody, OA-519 antibody, SDR27X1 antibody, FASN antibody, fj34h12 antibody, wu:fj34h12 antibody, Cgl0836 antibody, A630082H08Rik antibody, BcDNA:GH07626 antibody, BcDNA:gh07626 antibody, DM_7295848 antibody, Dmel\\CG3523 antibody, Fatty acid synthase antibody, anon-EST:Posey235 antibody, anon-EST:Posey43 antibody, anon-WO0138581.1 antibody, dFAS antibody, fas antibody, fatty acid synthase antibody, fatty acid synthase Fas antibody, type I polyketide synthase antibody, Fatty acid synthase Fas antibody, Fatty Acid SyNthase antibody, fatty-acid synthase antibody, fatty-acid synthase II antibody, fatty-acid synthase fas antibody, Fatty acid synthase 1 antibody, FASN antibody, fas antibody, Fasn antibody, BAD_RS01360 antibody, fasn antibody, fasn-1 antibody, NCgl0802 antibody, fasB antibody, MT2600 antibody, TBMG_01448 antibody, FASN1 antibody

Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Alias Symbols: FASN, FAS,

Protein Interaction Partner: UBC, FUS, HUWE1, SUMO3, SUMO2, STAU1, LGR4, SUMO1, MDM2, EED, KIAA1598, SIRT1, CAP1, TPM4, TPM3, FBXO6, YWHAQ, UBD, PHKG2, NPM1, LMNA, ILK, PRR12, VCAM1, NOS2, HSP90AB1, HSP90AA1, FN1, SMURF1, EIF4A3, PTPN11, MAGOH, TP53BP1, EMD, SHC1, AP2M1, CUL3, CDK2,

Protein Size: 2511

Gene ID: 2194

NCBI Accession: NP_004095

UniProt: P49327

Pathways: AMPK Signaling