NFATC4 antibody (N-Term)

Catalog No. ABIN5516118

Product Details anti-NFATC4 Antibody

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFATC4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PSIRITSISP TPEPPAALED NPDAWGDGSP RDYPPPEGFG GYREAGGQGG

Characteristics: This is a rabbit polyclonal antibody against NFATC4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NFATC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NFATC4

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Alternative Name: NFATC4 (NFATC4 Products)

Synonyms: si:dkeyp-66d1.4 antibody, NFATC4 antibody, 3110041H08Rik antibody, AW107667 antibody, AW546455 antibody, Nfat3 antibody, NF-ATc4 antibody, NFAT3 antibody, nuclear factor of activated T-cells 4 antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 antibody, NFATC4 antibody, nfatc4 antibody, Nfatc4 antibody

Background: This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.

Alias Symbols: NFATC4, NFAT3,

Protein Interaction Partner: ANKRD28, Dlg4, NR1I2, MAPK9, MAPK8, JUP, GPR22, CCNG1, LPIN1, CEBPA, GATA4, YWHAZ, MAPK14, CREBBP, YWHAQ,

Protein Size: 782

Gene ID: 4776

NCBI Accession: XP_005267762

Pathways: RTK Signaling, WNT Signaling