PLAGL1 antibody (Middle Region)

Catalog No. ABIN5516139

Product Details anti-PLAGL1 Antibody

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAGL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPESLASLHP SVSPGSPPPP LPNHKYNTTS TSYSPLASLP LKADTKGFCN

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLAGL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLAGL1

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Alternative Name: PLAGL1 (PLAGL1 Products)

Synonyms: PLAGL1 antibody, LOT1 antibody, ZAC antibody, ZAC1 antibody, Lot1 antibody, Zac1 antibody, PLAG1 like zinc finger 1 antibody, uncharacterized LOC100350914 antibody, pleiomorphic adenoma gene-like 1 antibody, PLAGL1 antibody, LOC100350914 antibody, Plagl1 antibody

Background: This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.

Alias Symbols: ZAC, LOT1, ZAC1

Protein Size: 411

Gene ID: 5325

NCBI Accession: NM_001080951, NP_001074420