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CYP11B2 antibody (N-Term)
CYP11B2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CYP11B2 Antibody
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Target
See all CYP11B2 Antibodies
CYP11B2
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
Binding Specificity
All epitopes for CYP11B2 antibodies
N-Term
Reactivity
All reactivities for CYP11B2 antibodies
Human
Host
All hosts for CYP11B2 antibodies
Rabbit
Clonality
All clonalities for CYP11B2 antibodies
Polyclonal
Conjugate
All conjugates for CYP11B2 antibodies
This CYP11B2 antibody is un-conjugated
Application
All applications for CYP11B2 antibodies
Western Blotting (WB)
Sequence
FEAMPQHPGN RWLRLLQIWR EQGYEHLHLE MHQTFQELGP IFRYNLGGPR
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CYP11B2
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Discover our top product CYP11B2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CYP11B2
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Target
CYP11B2
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
Alternative Name
CYP11B2 (CYP11B2 Products )
Synonyms
ALDOS antibody, CPN2 antibody, CYP11B antibody, CYP11BL antibody, CYPXIB2 antibody, P-450C18 antibody, P450C18 antibody, P450aldo antibody, Cpn2 antibody, Cyp11b antibody, Cyp11b-2 antibody, Cp45as antibody, Cyp11b3 antibody, RNCP45AS antibody, cytochrome P450 family 11 subfamily B member 2 antibody, cytochrome P450, family 11, subfamily b, polypeptide 2 antibody, aldosterone synthase antibody, cytochrome P450, family 11, subfamily B, polypeptide 2 antibody, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 antibody, CYP11B2 antibody, Cyp11b2 antibody
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. Alias Symbols: CPN2, ALDOS, CYP11B, CYP11BL, CYPXIB2, P450C18, P-450C18, P450aldo, Protein Size: 167
Gene ID
1585
NCBI Accession
NM_000498 , NP_000489
UniProt
P19099
Pathways
ACE Inhibitor Pathway , Metabolism of Steroid Hormones and Vitamin D , Steroid Hormone Biosynthesis , Regulation of Systemic Arterial Blood Pressure by Hormones , C21-Steroid Hormone Metabolic Process , Feeding Behaviour
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