CHRNB1 antibody (Middle Region)

Catalog No. ABIN5516456

Product Details anti-CHRNB1 Antibody

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GLILAQLISL NEKDEEMSTK VYLDLEWTDY RLSWDPAEHD GIDSLRITAE

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHRNB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNB1

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Alternative Name: CHRNB1 (CHRNB1 Products)

Synonyms: CHRNB1 antibody, ACHRB antibody, CHRNB antibody, CMS1D antibody, CMS2A antibody, SCCMS antibody, Acrb antibody, RNACRB1 antibody, Achr-2 antibody, cholinergic receptor nicotinic beta 1 subunit antibody, cholinergic receptor, nicotinic, beta 1 (muscle) antibody, acetylcholine receptor beta subunit antibody, cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) antibody, CHRNB1 antibody, chrnb1 antibody, ACHRB antibody, Chrnb1 antibody

Background: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Alias Symbols: ACHRB, CHRNB, CMS1D, CMS2A, CMS2C, SCCMS

Protein Size: 501

Gene ID: 1140

NCBI Accession: NM_000747, NP_000738

UniProt: P11230

Pathways: Synaptic Membrane