AP3M1 antibody (C-Term)

Catalog No. ABIN5516557

Product Details anti-AP3M1 Antibody

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3M1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TQGSYTFDPV TKVLTWDVGK ITPQKLPSLK GLVNLQSGAP KPEENPSLNI

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AP3M1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP3M1

Target: AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))

Alternative Name: AP3M1 (AP3M1 Products)

Synonyms: 1200013D09Rik antibody, C78982 antibody, R75378 antibody, P47a antibody, adaptor related protein complex 3 mu 1 subunit antibody, adaptor-related protein complex 3, mu 1 subunit antibody, AP3M1 antibody, Ap3m1 antibody

Background: The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants.

Protein Size: 418

Gene ID: 26985

NCBI Accession: NM_012095, NP_036227

UniProt: Q9Y2T2