CDC37 antibody (Middle Region)

Catalog No. ABIN5516682

Product Details anti-CDC37 Antibody

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC37 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KTEEDSEEVR EQKHKTFVEK YEKQIKHFGM LRRWDDSQKY LSDNVHLVCE

Characteristics: This is a rabbit polyclonal antibody against CDC37. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CDC37

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC37

Target: CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))

Alternative Name: CDC37 (CDC37 Products)

Synonyms: CG12019 antibody, CPDR-1 antibody, CPDR-2 antibody, DROCPDR antibody, Dmel\\CG12019 antibody, E(sev)3B antibody, cdc37 antibody, Afu4g10010 antibody, P50CDC37 antibody, p50 antibody, p50Cdc37 antibody, CG12019 gene product from transcript CG12019-RA antibody, cell division cycle 37 homolog antibody, Hsp90 co-chaperone Cdc37 antibody, Cdc37p antibody, cell division cycle 37 antibody, Cdc37 antibody, cdc37 antibody, AFUA_4G10010 antibody, CDC37 antibody

Background: The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Alias Symbols: CDC37, CDC37A,

Protein Interaction Partner: CDC25C, CDK1, HSP90AA1, AKT1, UBC, AURKA, SUMO2, PDZK1, HNRNPM, IKBKB, DNAJB1, HSP90AB1, FKBP5, FKBP4, FER, CTTN, CHUK, CDK4, SMYD3, FKBPL, UNC45A, CDC37L1, CDK11A, TTC9C, TARS2, RPAP3, CHORDC1, SYNE2, GLMN, TOMM34, USP19, AHSA1, DDX17, STUB1, AURKB, AIP,

Protein Size: 378

Gene ID: 11140

NCBI Accession: NP_008996

UniProt: Q16543