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GZMH antibody (Middle Region)

GZMH Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5516767
  • Target See all GZMH Antibodies
    GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
    Binding Specificity
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 31
    • 10
    • 2
    • 1
    Human
    Host
    • 27
    • 4
    Rabbit
    Clonality
    • 29
    • 2
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GZMH antibody is un-conjugated
    Application
    • 16
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RDDFVLTAAH CWGSSINVTL GAHNIKEQEP TQQFIPVKRP IPHPAYNPKN
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GZMH
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    Discover our top product GZMH Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
    Alternative Name
    GZMH (GZMH Products)
    Synonyms
    GZMH antibody, CCP-X antibody, CGL-2 antibody, CSP-C antibody, CTLA1 antibody, CTSGL2 antibody, granzyme H antibody, LOC617313 antibody, GZMH antibody
    Background
    This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.

    Alias Symbols: CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2

    Protein Size: 160
    Gene ID
    2999
    NCBI Accession
    NM_001270781, NP_001257710
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